Saturday, 18 February 2012

Latest in Scientific Cancer Treatments:





Latest in Scientific Cancer Treatments:
Nitrogen Mustard a compound similar to Mustard gas used in World War II can be considered as first chemotherapeutic agent used to fight cancer. This substance was first used in Dec 1942. Since then scientists have developed many chemotherapeutic agents with higher effectiveness and with lesser side effects.
Majority of people are aware of drastic side effects of cancer treatment which can be Chemotherapy, Radiation therapy or surgery.  Even the medical and scientific world is aware of the shortcomings of treatments which are used at present for Cancer treatment.
Following are some of the treatments which are under advanced stage of research. These tests are yet to get approval from authorities like FDA for actual use on humans but majority have shown very encouraging results in clinical or animal trials.
1.    Cancer Detecting Bra
2.     Microwaving Cancer
3.    Gold Nanorods Target Tumors
4.    Slowing Cancer Metabolism
5.    Fight Cancer with Purple Tomato
6.    Bombing Cancer with Virus
7.    Use of Newer contrast agents to fight cancer
8.    Detect cancer very early
9.    Killing of Stem cells of Breast cancer
10. Micro-bubbles activated by Ultrasound for killing cancer cells
11. Use of Electric field for killing cancer cells.
12. Use of Laser micro-scalpel to kill individual cancer cell 
13.Capturing cancer cells with magnets
14.Blocking Proliferation of Beta cells in Leukemia
15.Interferon based drugs to cure breast cancer
16.Latest endoscopic techniques to detect Pancreatic cancer at very early stage.

1. Cancer Detecting Bra
Scientists from the Centre for Research and Innovation at the University of Bolton in the United Kingdom, led by Professor Elias Siores, are using an existing technique for detecting breast cancer at its early stages.
An innovative bra currently under development might be able to detect the cancerous growths before they spread to additional areas, thus preventing metastasis and a more severe course of disease. The bra will notify the wearer of a problem and advise them to seek professional help.
Thermography is a type of infrared imaging science. A thermographic camera detects changes in the infrared radiation range and produces images of this radiation. The bra can use this technique because of the way cancerous tissue stands out metabolically against the healthy background tissues. Since tumors are constantly growing, they need a greater blood flow to supply them with nutrients and oxygen. A greater blood flow causes temperature to be elevated. This information is then analyzed by a separate controller unit which then sets off an alarm if the normal breast tissue temperature is exceeded.
2. Microwaving Cancer
Researchers from the Massachusetts Institute of Technology (MIT) have developed a therapeutic strategy against breast cancer, using chemotherapy and microwave energy. The method involves heating the cancer cells with special radar while conducting traditional chemotherapy treatment. This combination of microwave-generated heat strategy, known as thermotherapy, and traditional chemotherapy caused cancer patients' large tumors to shrink drastically and completely destroyed smaller tumors. The new method is now pending large scale clinical trials in Canada and the United States.
The microwave energy is generated using two applicators located near the patient's breast. This energy heats the cancer cells while leaving normal cells almost intact. The treatment attacks cancer cells that contain more water and ions than normal cells. The energy, applied in microwaves, makes the ions and water molecules vibrate and heat the cell. The cancer cells reach temperatures as high as 42.2 degrees Celsius (108 degrees Fahrenheit), making them inanimate. So far, the treatment has had very little side effects in clinical trials. 
The treatment developed in MIT showed promising results in several clinical trials. In the latest clinical trials, 15 patients with large cancerous tumors were treated using a combination of chemotherapy and thermotherapy. On average, the tumors decreased in size by 50 percent more than tumors treated with chemotherapy alone. In another series of clinical trials, which were conducted earlier on patients with small tumors, all the cancer cells were successfully eliminated prior to surgery using the combined thermotherapy-chemotherapy method. 
3. Gold Nanorods Target Tumors
Researchers at the Massachusetts Institute of Technology (MIT) have developed tiny gold rods capable of singling out tumorous cells and destroying them without damaging nearby healthy tissue. The gold nanorods absorb energy from near infrared light and then focus that energy at the tumors in the form of heat. The particles could also be used to locate and diagnose hidden or hard to reach tumors that don't necessarily show themselves with conventional imaging techniques.
4. Slowing Cancer Metabolism
Researchers at the Massachusetts Institute of Technology and Harvard University in Cambridge, Massachusetts are exploring new cancer drugs that work to slow or block cancer metabolism, effectively starving cancer cells to death. According to their study, the scientists identified a new way that such cells speed up their metabolism and divert energy to new cell creation. They are developing new drugs that slow or block this alternate mechanism to fight cancer.
5. Fight Cancer with Purple Tomato
Don't you just love it when simply eating something tasty helps you fight and prevent disease? Researchers from the John Innes Centre in Norwich, U.K. have genetically modified a tomato so that in addition to having a ravishing purple hue, it can also help prevent cancer.
Anthocyanins are naturally occurring pigments found at particularly high levels in berries such as blackberry, cranberry and chokeberry. These bioactive compounds offer protection against certain cancers, cardiovascular disease and age-related degenerative diseases. There is also some evidence that anthocyanins also have anti-inflammatory activity, promote visual acuity and hinder obesity and diabetes.
 But since most people eat a small variety of vegetables, scientists are investigating ways to increase the levels of health-promoting compounds in fruits and vegetables that are more commonly seen on our plates. (Eat More Vegetables)
6. Bombing Cancer with Virus
Researchers from the North Carolina State University have modified a common plant virus to deliver drugs specifically into cancer cells without harming the surrounding tissue. This discovery could increase the effectiveness of chemotherapy as well as reduce the side effects of the treatment.
Viruses are often used for the delivery of therapeutic drugs and recently the creation of tiny medical “smart bombs” has become one of the hottest areas of research in nanotechnology. These bombs are able to attach themselves to specific cells and deliver a chemical substance. While such devices would be useful to treat a variety of disease, they are usually used to fight cancer.
7. Use of Newer contrast agents to fight cancer
Researcher Kristina Djanashvili, from Delft University of Technology in the Netherlands, has developed a new contrast agent which can be used in MRI scans in order to better identify tumors. Her discovery should lead to earlier and more precise cancer detection and treatment.
Kristina Djanashvili, a postgraduate researcher from TU Delft, has recently developed a new contrast agent with greater tumor affinity and contrast induction characteristics. Greater affinity means that a smaller amount of cancerous growth can be picked up by the MRI and tumors can be found at earlier stages and visualized more accurately than by use of existing substances
8. Detect cancer very early
Scientists from Stanford University have developed a device that can scan blood and find signs of cancer, even at its earliest stages. Early detection will allow early treatment and greatly improve the survival chances of patients.
Stanford University scientists have developed a system based on MagArray's biodetection chips that are capable of detecting cancer-associated proteins in a blood serum sample in less than an hour. MagArray is a startup company in the Panorama Institute for Molecular Medicine, a not-for-profit incubator in Sunnyvale, California. The device was created using magnetic nanotechnology and can detect cancer proteins with a far greater sensitivity than that of existing commercial devices. As a result of this enhanced sensitivity, cancer can be detected at a very early stage, while there are relatively few proteins released into the bloodstream.
9. Killing of Stem cells of Breast cancer
Researchers at the Broad Institute and Whitehead Institute (both in Cambridge, Massachusetts) have discovered a chemical that kills breast cancer stem cells in mice. These cells are believed to be the cause of the spread of cancer and also of the recurrence of some cancers that previously appeared to be eradicated. By killing these stem cells, both the spread and reappearance of cancers could be decreased and, ultimately, prevented.
10. Micro-bubbles activated by Ultrasound for killing cancer cells
Philips is currently developing a new technology, which will administer drugs into specific locations using Ultrasound-Activated Microbubbles. This new technology will increase the effectiveness and reduce the side effects of chemotherapy for several types of cancer.
The system is designed to help ultrasound operators locate tumours based on their density and the tumour-specific network of small blood vessels. When the tumour is located, the system shatters the shells of the microbubbles by means of a focused, high-energy ultrasound pulse. Once the shells are destroyed, the contents of the microbubbles spill into the surrounding area and the drugs reach the tumour directly instead of going through the whole bloodstream. This localized release technique prevents the drugs from influencing other systems in the body, thus preventing gruelling side-effects and improving the quality of life of the patient undergoing chemotherapy.
11. Use of Electric field for killing cancer cells.
A group of scientists headed by Yoram Palti from the Technion Institute in Israel, succeeded in killing dividing cells without harming non-dividing ones using electrical charges. It turns out that an electrical field in a small enough voltage doesn't damage living cells. The scientists used this fact to treat a cancerous organ with an altering current (AC) electrical field. Using the AC electrical field, normal cells remain unharmed while the dividing cancerous cells are destroyed.

The researches as mentioned above and many similar researches going on around the world will one day certainly result in complete cure of all types of Cancers.

Readers are requested to share any similar scientific information which they may come across.

Happy Mind Is Healthy Mind

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